Name | tetradecylthioacetic acid |
Synonyms | TTA Tetradcylthioacetic Acid TETRADECYLTHIOACETIC ACID tetradecylthioacetic acid TETRADECYLMERCAPTO ACETIC ACID THTRADECYLMERCAPTO ACETIC ACID (tetradecylsulfanyl)acetic acid Tetradecylthioacetic acid (TTA) 1-(carboxymethylthio)tetradecane 1-MONO(CARBOXYMETHYLTHIO)TETRADECANE |
CAS | 2921-20-2 |
EINECS | 1308068-626-2 |
InChI | InChI=1/C16H32O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-19-15-16(17)18/h2-15H2,1H3,(H,17,18) |
Molecular Formula | C16H32O2S |
Molar Mass | 288.49 |
Density | 0.957±0.06 g/cm3(Predicted) |
Melting Point | 65-73°C |
Boling Point | 402.6±28.0 °C(Predicted) |
Flash Point | 197.3°C |
Solubility | DMSO: ≥22mg/mL, soluble |
Vapor Presure | 1.32E-07mmHg at 25°C |
Appearance | Solid |
Color | white |
pKa | 3.85±0.10(Predicted) |
Storage Condition | -20°C Freezer |
Refractive Index | 1.481 |
Physical and Chemical Properties | Melting Point 65-73°C |
WGK Germany | 3 |
RTECS | AJ5087000 |
application | decyl thioacetic acid is an intermediate in organic synthesis and pharmaceutical, which can be used in laboratory research and development and chemical medicine research and development. |
use | TTA is a novel thio-fatty acid which cannot undergo beta-oxidation. It induces apoptosis in IPC-81 leukemia cells via depolarization of mitochondrial membrane potential and inhibits glioma cell proli feration. TTA completely prevents high fat diet-induced insulin resistance and adiposity in Wistar rats. Activates rodent PPAR with rank order PPAR α>PPAR δ>PPAR γ. |